261-5113-00L Computational Challenges in Medical Genomics (Spring 2021)

This seminar discusses recent relevant contributions to the fields of computational genomics, algorithmic bioinformatics, statistical genetics and related areas. Each participant will hold a presentation and lead the subsequent discussion.

Preparing and holding a scientific presentation in front of peers is a central part of working in the scientific domain. In this seminar, the participants will learn how to efficiently summarize the relevant parts of a scientific publication, critically reflect its contents, and summarize it for presentation to an audience. The necessary skills to succesfully present the key points of existing research work are the same as needed to communicate own research ideas. In addition to holding a presentation, each student will both contribute to as well as lead a discussion section on the topics presented in the class.

The topics covered in the seminar are related to recent computational challenges that arise from the fields of genomics and biomedicine, including but not limited to genomic variant interpretation, genomic sequence analysis, compressive genomics tasks, single-cell approaches, privacy considerations, statistical frameworks, etc. Both recently published works contributing novel ideas to the areas mentioned above as well as seminal contributions from the past are amongst the list of selected papers.


Until further notice, the seminar will be held as an online event, using the Zoom video conference platform. The time of the seminar remains Mondays 14-16. Further details on how to connect to the conference, will be communicated via e-mail to all registered participants prior to the first session. 

Once the regulations allow for in-person teaching again, we will communicate this here. In case of in-person teaching, the seminar will be held at ETH in CAB G 57 (link to location). Mondays 14-16.

Course Overview

Date Topic Course Material / Literature
22.02.2021 Introduction Session 1 - Slides
Session 1 - Video
01.03.2021 No session (Preparation)
08.03.2021 No session (Preparation)
15.03.2021 Presentations 1 & 2 Session 2 - Slides
Session 2 - Video
Presentation 1
Presentation 2
22.03.2021 Presentations 3 & 4 Session 3 - Video
Presentation 3
Presentation 4
29.03.2021 No session
05.04.2021 No session (Easter)
12.04.2021 Presentations 5 & 6 Session 4 - Video
Presentation 5
Presentation 6
29.03.2021 No session (Sechseläuten)
26.04.2021 Presentations 7 & 8 Session 5 - Video
Presentation 7
Presentation 8
03.05.2021 Presentations 9 & 10 Session 6 - Video
Presentation 9
Presentation 10
10.05.2021 Presentations 11 & 12 Session 7 - Video
Presentation 11
Presentation 12
17.05.2021 No session
24.05.2021 No session (Pentecost)
31.05.2021 No session


Please use the signup-sheet to choose a paper for presentation. The spreadsheet will become writable during the first seminar session. Please use exactly one row and do not remove any names from rows that are already assigned.